Updated Summary of the Preprint: “A maternal-fetal PIEZO1 incompatibility as a barrier to Neanderthal-modern human admixture”
This work reframes Neanderthal demise as multifactorial with ecological pressures and cryptic but insidious genetics and the work bridges evolution, physiology and obstetrics. It posits PIEZO1 as a “speciation gene,” with echoes in modern reproductive health and may explain the scarcity of Neanderthal alleles in fertility-related genes and the absence »